Gene Expression Data
Assay Details
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Assay
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Reference:
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J:273625
Takahashi M, et al., An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6361652
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Gene symbol:
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Timp1
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Gene name:
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tissue inhibitor of metalloproteinase 1
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Probe:
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Timp1 cDNA4
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2d:
embryonic day 14.5
(more  )
Specimen
2d:
(close  )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: mandible ramus |
Present |
Regionally restricted |
2d
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Expression is in the inner region of the condylar anlage.
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| TS22: periosteum |
Present |
Regionally restricted |
2d
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Expression is in the periosteum of the condylar anlage.
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Specimen
2i:
embryonic day 15.5
(more )
Specimen
2i:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: mandible ramus |
Present |
Regionally restricted |
2i
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Expression is in the periosteum/perichondrium and is weak in a region posterior to the newly formed condylar cartilage consisting of a mesenchymal cell condensation.
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| TS23: periosteum |
Present |
Regionally restricted |
2i
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Expression is in the inner layer of the periosteum of the condylar anlage.
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| TS23: perichondrium |
Present |
Regionally restricted |
2i
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Expression is in the inner layer of the perichondrium of the condylar anlage.
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Specimen
3d:
embryonic day 16.5
(more )
Specimen
3d:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: mandible condylar process |
Present |
Regionally restricted |
3d'
,
3d
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Expression is in the inner layer of the fibrous cell zone and polymorphic cell zone and in the perichondrium and periosteum.
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| TS24: perichondrium |
Present |
Regionally restricted |
3d
,
3d'
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Expression is in the inner layer of the perichondrium and periosteum of the condylar anlage.
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| TS24: periosteum |
Present |
Regionally restricted |
3d
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3d'
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Expression is in the inner layer of the perichondrium and periosteum of the condylar anlage.
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Specimen
3j:
embryonic day 18.5
(more )
Specimen
3j:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: mandible condylar process |
Present |
Regionally restricted |
3j
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3j'
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Expression is in the fibrous cell zone and polymorphic cell zone and is absent in the articular disc. Expression is absent in the anlagen of the articular disc.
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| TS26: perichondrium |
Present |
Regionally restricted |
3j'
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3j
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS26: periosteum |
Present |
Regionally restricted |
3j'
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3j
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
4d:
embryonic day 12.5
(more )
Specimen
4d:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4i:
embryonic day 13.5
(more )
Specimen
4i:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4n:
embryonic day 14.5
(more )
Specimen
4n:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: periosteum |
Weak |
Regionally restricted |
4n
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Expression is in the periosteum and is absent in the perichondrium of the tibia.
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| TS22: tibia cartilage condensation |
Weak |
Regionally restricted |
4n
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Expression is in the periosteum and is absent in the perichondrium of the tibia.
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Specimen
5d:
embryonic day 16.5
(more )
Specimen
5d:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: periosteum |
Present |
Regionally restricted |
5d
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Expression is in the periosteum of the developing sphenoid bone cartilage.
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| TS24: sphenoid bone |
Present |
Regionally restricted |
5d
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Expression is in the periosteum of the developing sphenoid bone cartilage.
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Analysis Tools