Gene Expression Data
Assay Details
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Assay
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Reference:
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J:273625
Takahashi M, et al., An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6361651
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Gene symbol:
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Mmp14
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Gene name:
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matrix metallopeptidase 14 (membrane-inserted)
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Probe:
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Mmp14 cDNA3
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2c:
embryonic day 14.5
(more  )
Specimen
2c:
(close  )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: mandible ramus |
Present |
Regionally restricted |
2c
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Expression is in the condylar anlage and the periosteum.
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| TS22: periosteum |
Present |
Regionally restricted |
2c
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Expression is in the condylar anlage and the periosteum.
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Specimen
2h:
embryonic day 15.5
(more )
Specimen
2h:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: mandible ramus |
Present |
Regionally restricted |
2h
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Expression is in the inner layer of the periosteum/perichondrium and is weak in a region posterior to the newly formed condylar cartilage consisting of a mesenchymal cell condensation.
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| TS23: periosteum |
Present |
Regionally restricted |
2h
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Expression is in the inner layer of the periosteum of the condylar anlage.
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| TS23: perichondrium |
Present |
Regionally restricted |
2h
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Expression is in the inner layer of the perichondrium and periosteum of the condylar anlage.
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Specimen
3c:
embryonic day 16.5
(more )
Specimen
3c:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: mandible condylar process |
Present |
Regionally restricted |
3c
,
3c'
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Expression is in the inner layer of the fibrous cell zone and polymorphic cell zone and in the perichondrium and periosteum. Expression is in the bone collar in large cells, corresponding to multinucleated osteoclasts/chondroclasts.
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| TS24: perichondrium |
Present |
Regionally restricted |
3c
,
3c'
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Expression is in the inner layer of the perichondrium and periosteum of the condylar anlage.
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| TS24: periosteum |
Present |
Regionally restricted |
3c
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3c'
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Expression is in the inner layer of the perichondrium and periosteum of the condylar anlage.
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Specimen
3i:
embryonic day 18.5
(more )
Specimen
3i:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: mandible condylar process |
Present |
Regionally restricted |
3i
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3i'
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Expression is in the fibrous cell zone and polymorphic cell zone and is absent in the articular disc. Expression is absent in the anlagen of the articular disc.
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| TS26: perichondrium |
Present |
Regionally restricted |
3i'
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3i
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS26: periosteum |
Present |
Regionally restricted |
3i'
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3i
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
4c:
embryonic day 12.5
(more )
Specimen
4c:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4h:
embryonic day 13.5
(more )
Specimen
4h:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: perichondrium |
Present |
Regionally restricted |
4h
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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| TS21: tibia-fibula pre-cartilage condensation |
Present |
Regionally restricted |
4h
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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Specimen
4m:
embryonic day 14.5
(more )
Specimen
4m:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: perichondrium |
Present |
Regionally restricted |
4m
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia. Expression is weaker in the perichondrium and restricted to the inner layer of the periosteum.
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| TS22: periosteum |
Present |
Regionally restricted |
4m
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia. Expression is weaker in the perichondrium and restricted to the inner layer of the periosteum.
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| TS22: tibia cartilage condensation |
Present |
Regionally restricted |
4m
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia. Expression is weaker in the perichondrium and restricted to the inner layer of the periosteum.
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Specimen
4q:
embryonic day 15.5
(more )
Specimen
4q:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
Regionally restricted |
4q
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Expression is in the primary ossification center, in osteoclasts/chondroclasts and bone marrow cells.
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Specimen
5c:
embryonic day 16.5
(more )
Specimen
5c:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: perichondrium |
Present |
Regionally restricted |
5c
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Expression is in the perichondrium (weak) and in the bone collar of the developing sphenoid bone cartilage.
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| TS24: sphenoid bone |
Present |
Regionally restricted |
5c
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Expression is in the perichondrium (weak) and in the bone collar of the developing sphenoid bone cartilage.
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| TS24: periosteum |
Present |
Regionally restricted |
5c
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Expression is the inner layer of the periosteum of the developing sphenoid bone cartilage.
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Analysis Tools