Gene Expression Data
Assay Details
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Assay
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Reference:
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J:273625
Takahashi M, et al., An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6361621
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Gene symbol:
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Mmp2
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Gene name:
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matrix metallopeptidase 2
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Probe:
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Mmp2 cDNA2
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2b:
embryonic day 14.5
(more  )
Specimen
2b:
(close  )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: mandible |
Present |
Regionally restricted |
2b
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Expression is in the periosteum of mandibular bone.
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| TS22: periosteum |
Present |
Regionally restricted |
2b
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Expression is in the periosteum of mandibular bone.
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| TS22: mandible ramus |
Present |
Regionally restricted |
2b
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Expression is in the condylar anlage and is stronger in the outer region that is continuous with the periosteum.
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Specimen
2g:
embryonic day 15.5
(more )
Specimen
2g:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: mandible ramus |
Present |
Regionally restricted |
2g
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Expression is in a region posterior to the newly formed condylar cartilage consisting of a mesenchymal cell condensation.
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| TS23: perichondrium |
Present |
Regionally restricted |
2g
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS23: periosteum |
Present |
Regionally restricted |
2g
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
3b:
embryonic day 16.5
(more )
Specimen
3b:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: mandible condylar process |
Present |
Regionally restricted |
3b'
,
3b
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Expression is in the fibrous cell zone and polymorphic cell zone, and is weak in the flattened cell zone. Expression is absent in the upper and lower hypertrophic cell zone.
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| TS24: perichondrium |
Strong |
Regionally restricted |
3b
,
3b'
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS24: periosteum |
Strong |
Regionally restricted |
3b
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3b'
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
3h:
embryonic day 18.5
(more )
Specimen
3h:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: mandible condylar process |
Present |
Regionally restricted |
3h'
,
3h
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Expression is in the fibrous cell zone and polymorphic cell zone and in the anlage of the articular disc, and is weak in the flattened cell zone. Expression is in the anlagen of the articular disc.
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| TS26: perichondrium |
Present |
Regionally restricted |
3h'
,
3h
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS26: periosteum |
Present |
Regionally restricted |
3h'
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3h
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
4b:
embryonic day 12.5
(more )
Specimen
4b:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4g:
embryonic day 13.5
(more )
Specimen
4g:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: perichondrium |
Present |
Regionally restricted |
4g
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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| TS21: tibia-fibula pre-cartilage condensation |
Present |
Regionally restricted |
4g
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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Specimen
4l:
embryonic day 14.5
(more )
Specimen
4l:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: perichondrium |
Strong |
Regionally restricted |
4l
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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| TS22: periosteum |
Strong |
Regionally restricted |
4l
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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| TS22: tibia cartilage condensation |
Strong |
Regionally restricted |
4l
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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Specimen
5b:
embryonic day 16.5
(more )
Specimen
5b:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: perichondrium |
Present |
Regionally restricted |
5b
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Expression is in the perichondrium and the bone collar of the developing sphenoid bone cartilage.
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| TS24: sphenoid bone |
Present |
Regionally restricted |
5b
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Expression is in the perichondrium and the bone collar of the developing sphenoid bone cartilage.
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Analysis Tools