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Gene Expression Data
Assay Details
Assay
Reference: J:106405 Mackay DR, et al., The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol. 2006 Mar 1;291(1):38-52
Assay type: RNA in situ
MGI Accession ID: MGI:6360621
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5B +/-: embryonic day 8.5; Ovol2tm1Xdai/Ovol2+ (more )
Structure Level Pattern Image Note
TS13: neural plate Present Regionally restricted 5B +/- Expression in anterior neural ridge at rostral margin of neural plate.
TS13: midbrain-hindbrain junction Present Regionally restricted 5B +/- Expression in isthmic organizer at midbrain-hindbrain boundary.
Specimen 5B -/-: embryonic day 8.5; Ovol2tm1Xdai/Ovol2tm1Xdai (more )
Structure Level Pattern Image Note
TS13: midbrain-hindbrain junction Present Regionally restricted 5B -/- Authors report largely normal A-P brain patterning in mutants.
TS13: neural plate Present Regionally restricted 5B -/- Authors report largely normal A-P brain patterning in mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory