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Gene Expression Data
Assay Details
Assay
Reference: J:275842 Garnai SJ, et al., Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. PLoS Genet. 2019 May;15(5):e1008130
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6360315
Gene symbol: Tmem98
Gene name: transmembrane protein 98
Antibody: TMEM98 Antibody (14731-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 8C left: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pigmented retinal epithelium Present 8C left
Specimen 8C middle: embryonic day 15.5; Myrftm1Barr/Myrf+, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: pigmented retinal epithelium Present 8C middle
Specimen 8C right: embryonic day 15.5; Myrftm1Barr/Myrftm1Barr, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: pigmented retinal epithelium Absent 8C right
Specimen S10 P3 upper: postnatal day 3; Myrftm1Barr/Myrf+ (more )
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present S10_P3 upper
Specimen S10 P3 middle: postnatal day 3; Myrftm1Barr/Myrf+, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present S10_P3 middle
Specimen S10 P3 lower: postnatal day 3; Myrftm1Barr/Myrftm1Barr, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present S10_P3 lower A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern.
Specimen S10 P14 upper: postnatal day 14; Myrftm1Barr/Myrf+ (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P14 upper
Specimen S10 P14 middle: postnatal day 14; Myrftm1Barr/Myrf+, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P14 middle
Specimen S10 P14 lower: postnatal day 14; Myrftm1Barr/Myrftm1Barr, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P14 lower A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern.
Specimen S10 P22 upper: postnatal day 22; Myrftm1Barr/Myrf+ (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P22 upper
Specimen S10 P22 middle: postnatal day 22; Myrftm1Barr/Myrf+, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P22 middle
Specimen S10 P22 lower: postnatal day 22; Myrftm1Barr/Myrftm1Barr, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S10_P22 lower A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory