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Gene Expression Data
Assay Details
Assay
Reference: J:104974 MacDonald JL, et al., Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Dev Biol. 2005 Dec 15;288(2):461-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6360286
Gene symbol: Dnmt3a
Gene name: DNA methyltransferase 3A
Antibody: anti-Dnmt3a
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5B: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Krt5 (assay MGI:6360283).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5B Not co-expressed with cytokeratin 5/6 in horizontal basal cells.
Specimen 5C: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5C Not co-expressed with Pcna in globose basal cells.
Specimen 5D: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Gap43 (assay MGI:6360277).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5D Expression in immature and mature neuronal cells.
Specimen 5E: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3a; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present 5E Co-expression with Tubb3 throughout development of olfactory epithelium.
Specimen 5F: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3a; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 5F Co-expression with Tubb3 throughout development of olfactory epithelium.
Specimen 5H: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 5H Co-expression with Tubb3 in majority of cells.
Specimen 5I: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3a; green - Omp (assay MGI:6360278).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present Regionally restricted 5I Expression in majority of Omp-expressing cells.
Specimen 5J: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3a; green - Omp (assay MGI:6360278).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5J Expression in majority of Omp-expressing cells.
Specimen 5L: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Omp (assay MGI:6360278).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5L Expression in only a subset of Omp-expressing cells.
Specimen 6G: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3a: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present Regionally restricted 6G Exclusive expression in most apical cells.
Specimen 6H: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3a: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 6H Exclusive expression in most apical cells.
Specimen 6I: postnatal adult (more )
Note: Double labeled: red - Dnmt3a: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 6I
Specimen 8B: postnatal adult (more )
Note: Double labeled: red - Dnmt3a; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS28: vomeronasal organ epithelium Present Regionally restricted 8B No co-expressed with Pcna in vomeronasal organ, but expressed in more apical cell layers.
Specimen 8D: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3a; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS25: pigmented retinal epithelium Present 8D
TS25: neural retina Present Regionally restricted 8D Expression in subpopulation of Tubb3-expressing neurons in granule cell layer.
Specimen 8G: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3a; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS25: lateral ventricle Present Regionally restricted 8G Co-expression with Pcna in lateral ventricle.
TS25: main olfactory bulb Present Regionally restricted 8G Expression in PCNA-expressing and nonexpressing cells in olfactory bulb.
TS25: cerebral cortex Present Regionally restricted 8G Expression in non-PCNA-expressing cells in developing cortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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