L1cam Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:259672 Peng J, et al., Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait. Dev Dyn. 2018 Apr;247(4):620-629
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6358770
Gene symbol:	L1cam
Gene name:	L1 cell adhesion molecule

Antibody:	anti-NCAM L1 (clone 324)
Detection system:	Alexa Fluor 488

Results

2C ©

2C' ©

Specimen 2C/C': embryonic day 11.5; Dcc^tm1Nki/Dcc⁺, Tg(Hoxb8-cre)1403Uze/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: future spinal cord	Present	Regionally restricted	2C' , 2C	Expression in post-crossing commissural axons forming a thick commissure at the floor plate.

2D ©

2D' ©

Specimen 2D/D': embryonic day 11.5; Dcc^tm1Nki/Dcc^tm1Nki, Tg(Hoxb8-cre)1403Uze/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: future spinal cord	Trace	Regionally restricted	2D' , 2D	Severely reduced post-crossing commissural neurons at floor plate and crossed axons in the ventral funiculus.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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