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Gene Expression Data
Assay Details
Assay
Reference: J:104611 Moore-Scott BA, et al., Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev Biol. 2005 Feb 15;278(2):323-35
Assay type: RNA in situ
MGI Accession ID: MGI:6356729
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe77
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 8A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch ectoderm Present 8A
TS17: 1st branchial arch mesenchyme Present 8A
TS17: 2nd branchial arch ectoderm Present 8A
TS17: 2nd branchial arch mesenchyme Present 8A
TS17: 2nd branchial groove ectoderm Present Regionally restricted 8A Expression in ventral portion of second cleft ectoderm.
TS17: 2nd branchial pouch Present Regionally restricted 8A Expression in dorsal portion of second pouch and surrounding mesenchyme.
TS17: 3rd branchial pouch Present Regionally restricted 8A Expression in ventral/posterior domain of the third pouch.
Specimen 8B: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Absent 8B Expression lost in remnant of first arch and from second arch.
TS17: 2nd branchial arch Weak Regionally restricted 8B Expression lost in remnant of first arch and from second arch.
TS17: 2nd branchial groove Present 8B Expression in second cleft and pouch remain similar to control embryos.
TS17: 2nd branchial pouch Present 8B Expression in second cleft and pouch remain similar to control embryos.
TS17: 3rd branchial pouch endoderm Present Widespread 8B Expression expanded throughout endoderm of thrid pouch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory