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Gene Expression Data
Assay Details
Assay
Reference: J:104611 Moore-Scott BA, et al., Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev Biol. 2005 Feb 15;278(2):323-35
Assay type: RNA in situ
MGI Accession ID: MGI:6356725
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 2nd branchial pouch endoderm Present 4A
TS15: 3rd branchial pouch endoderm Present 4A
TS15: branchial groove ectoderm Present 4A Expression in ectoderm of clefts.

Specimen 4B: embryonic day 9.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS15: 2nd branchial pouch endoderm Present 4B Authors report normal expression in mutant embryos.
TS15: 3rd branchial pouch endoderm Present 4B Authors report normal expression in mutant embryos.
TS15: branchial groove ectoderm Present 4B Authors report normal expression in mutant embryos.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial pouch endoderm Present 4C
TS17: 3rd branchial pouch endoderm Present 4C
TS17: 4th branchial pouch endoderm Present 4C
TS17: branchial groove ectoderm Present 4C Expression in ectoderm of clefts.

Specimen 4D: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: 2nd branchial pouch Strong 4D Authors state expression failed to be downregulated in the second pouch and appears elevated in relation to the third pouch, as compared to littermate control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory