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Gene Expression Data
Assay Details
Assay
Reference: J:104160 Tole S, et al., Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
Assay type: RNA in situ
MGI Accession ID: MGI:6356603
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe60
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: telencephalon septum Present Regionally restricted 2A Authors report characteristic pattern of expression in septum.
Specimen 2B: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: intercerebral commissure Present Regionally restricted 2B Expression in anterior commissure, corpus callosum and hippocampal commissure.
TS24: corpus callosum Present 2B Expression in anterior commissure, corpus callosum and hippocampal commissure.
TS24: hippocampal commissure Present 2B Expression in anterior commissure, corpus callosum and hippocampal commissure.
Specimen 2C: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: intercerebral commissure Present 2C Expression in anterior commissure axons extending toward midline.
Specimen 2D: embryonic day 16.5; Fgfr3tm1Led/Fgfr3tm1Led (more )
Structure Level Pattern Image Note
TS24: telencephalon septum Present Regionally restricted 2D Authors report no appreciable defects compared to control.
Specimen 2E: embryonic day 16.5; Fgfr3tm1Led/Fgfr3tm1Led (more )
Structure Level Pattern Image Note
TS24: intercerebral commissure Present Regionally restricted 2E Authors report no appreciable defects compared to control.
TS24: corpus callosum Present 2E Authors report no appreciable defects compared to control.
TS24: hippocampal commissure Present 2E Authors report no appreciable defects compared to control.
Specimen 2F: embryonic day 16.5; Fgfr3tm1Led/Fgfr3tm1Led (more )
Structure Level Pattern Image Note
TS24: intercerebral commissure Present Regionally restricted 2F Expression in anterior commissure axons extending toward midline.
Specimen 2G: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: telencephalon septum Absent 2G Authors report expression in septum appears to be missing.
Specimen 2H: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: corpus callosum Absent 2H Expression in corpus callosum and hippocampal commissure are not detectable.
TS24: hippocampal commissure Absent 2H Expression in corpus callosum and hippocampal commissure are not detectable.
Specimen 2I: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: intercerebral commissure Present Regionally restricted 2I Expression in anterior commissure axons arresting in lateral region.
Specimen 2J: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: telencephalon septum Absent 2J Authors report expression in septum appears to be missing.
Specimen 2K: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: corpus callosum Absent 2K Expression in corpus callosum and hippocampal commissure are not detectable.
TS24: hippocampal commissure Absent 2K Expression in corpus callosum and hippocampal commissure are not detectable.
Specimen 2L: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: intercerebral commissure Present Regionally restricted 2L Expression in anterior commissure axons arresting in lateral region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory