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Gene Expression Data
Assay Details
Assay
Reference: J:104160 Tole S, et al., Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6356602
Gene symbol: Gfap
Gene name: glial fibrillary acidic protein
Antibody: anti-GFAP (Z0334)
Detection system: Texas Red
Results
Specimen E14.5 control not shown: embryonic day 14.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS22: brain Absent Expression undetectable at E14.5
Specimen E15.5 control not shown: embryonic day 15.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS23: brain Trace Expression only faintly discernable at E15.5.
Specimen 3 Control Anterior: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: brain white matter Present Regionally restricted 3_Control Anterior Expression in midline zipper glia.
Specimen 3 Control (middle): embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: indusium griseum Present Regionally restricted 3_Control (middle) Expression in indusium griseum glia and glial wedge.
TS24: brain white matter Present Regionally restricted 3_Control (middle) Expression in glial wedge.
Specimen 3 Control Posterior: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: hippocampal commissure Present Regionally restricted 3_Control Posterior Expression in indusium griseum and hipoocampal glia.
TS24: indusium griseum Present Regionally restricted 3_Control Posterior Expression in indusium griseum and hipoocampal glia.
Specimen 3 Mutant Anterior: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: brain white matter Present Regionally restricted 3_Mutant Anterior No expression in midline zipper glia.
Specimen 3 Mutant (middle): embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: indusium griseum Absent 3_Mutant (middle) No expression in indusium griseum glia.
TS24: brain white matter Present Regionally restricted 3_Mutant (middle) No expression in glial wedge.
Specimen 3 Mutant Posterior: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Fgfr3tm1Led/Fgfr3tm1Led, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: hippocampal commissure Present Regionally restricted 3_Mutant Posterior Expression in hipoocampal glia.
Specimen E17.5 control not shown: embryonic day 17.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS25: hippocampal commissure Present Regionally restricted Expression in hipoocampal glia.
Specimen E17.5 mutant not shown: embryonic day 17.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: hippocampal commissure Present Regionally restricted Expression in hipoocampal glia.
Specimen 7A: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: indusium griseum Present 7A
Specimen 7B: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: indusium griseum Present 7B
Specimen 7C: embryonic day 16.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS24: brain white matter Present Regionally restricted 7C Expression in midline zipper.
Specimen 7D: embryonic day 16.5; Fgfr1tm1Upir/Fgfr1+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: brain white matter Present Regionally restricted 7D Expression in midline zipper.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory