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Gene Expression Data
Assay Details
Assay
Reference: J:271089 Cheng C, et al., Characterization of a Mouse Model of Borjeson-Forssman-Lehmann Syndrome. Cell Rep. 2018 Nov 6;25(6):1404-1414.e6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6355451
Gene symbol: Phf6
Gene name: PHD finger protein 6
Antibody: anti-Phf6
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1D - E14: embryonic day 14.0 (more )
Note: Double labeled: green - Phf6; red - Bcl11b (assay MGI:6355455)
Structure Level Pattern Image Note
TS22: cortical plate Present Regionally restricted 1D E14 triple label , 1D E14 PHF6 Expression is co-localized with the layer V marker, Bcl11b.
Specimen 1D - E18: embryonic day 18.0 (more )
Note: Double labeled: green - Phf6; red - Bcl11b (assay MGI:6355455)
Structure Level Pattern Image Note
TS26: cortical plate Present Widespread 1D E18 triple label , 1D E18 PHF6 Expression is seen in all layers.
Specimen 1D - P2: postnatal day 2 (more )
Note: Double labeled: green - Phf6; red - Bcl11b (assay MGI:6355455)
Structure Level Pattern Image Note
TS27: cerebral cortex Present 1D P2 triple label , 1D P2 PHF6
Specimen 1D - P6: postnatal day 6 (more )
Note: Double labeled: green - Phf6; red - Bcl11b (assay MGI:6355455)
Structure Level Pattern Image Note
TS28: cerebral cortex Present 1D P6 PHF6 , 1D P6 triple label
Specimen 1F - Control: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present 1F Control
Specimen 1F - C99F: embryonic day 14.5; Phf6em1Azbi/Y (more )
Structure Level Pattern Image Note
TS22: cortical plate Present 1F PHF6 C99F Expression levels are substantially reduced in the mutant.
Specimen S1C - Control: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present S1C Control
Specimen S1C - C99F: postnatal day 0; Phf6em1Azbi/Y (more )
Structure Level Pattern Image Note
TS27: cortical plate Present S1C C99F Expression levels are substantially reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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