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Gene Expression Data
Assay Details
Assay
Reference: J:218234 Wurm S, et al., Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev. 2015 Jan 15;29(2):144-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6331278
Gene symbol: Flg
Gene name: filaggrin
Antibody: Anti-Filaggrin
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1F left lower: embryonic day 17.5; Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+ (more )
Note: Double labeled: red - Flg; green - Krt5 (assay MGI:6331272).
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 1F lower left Expressed in terminal epidermal differentiated cells.
Specimen 2C Co lower: embryonic day 17.5; Fosl2tm2Wag/Fosl2tm2Wag (more )
Note: Double labeled: red - Flg; green - Krt5 (assay MGI:6331272).
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 2C lower left Expressed in terminal epidermal differentiated cells.
Specimen 2C deltasb lower: embryonic day 17.5; Fosl2tm2Wag/Fosl2tm2Wag, Tg(Foxn1-cre)1Tbo/0 (more )
Note: Conditional mutant. Double labeled: red - Flg; green - Krt5 (assay MGI:6331272).
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 2C lower middle Expressed in terminal epidermal differentiated cells. Significantly reduced expression compared with the control.
Specimen 2C deltaep lower: embryonic day 17.5; Fosl2tm2Wag/Fosl2tm2Wag, Tg(KRT5-cre)1Tak/0 (more )
Note: Conditional mutant. Double labeled: red - Flg; green - Krt5 (assay MGI:6331272).
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 2C lower right Expressed in terminal epidermal differentiated cells. Significantly reduced expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory