Fosl2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:218234 Wurm S, et al., Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev. 2015 Jan 15;29(2):144-56
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6331249
Gene symbol:	Fosl2
Gene name:	fos-like antigen 2

Antibody:	Fra-2 (286C/B5)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1D ©

Specimen 1D: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: epidermis	Present	Graded	1D	Expressed in all epidermal layers. A gradient with the highest expression in terminally differentiated keratinocytes was observed.

2A left ©

Specimen 2A Co: embryonic day 17.5; Fosl2^tm2Wag/Fosl2^tm2Wag (more

)

Structure	Level	Pattern	Image	Note
TS25: epidermis	Present		2A left

2A middle ©

Specimen 2A deltasb: embryonic day 17.5; Fosl2^tm2Wag/Fosl2^tm2Wag, Tg(Foxn1-cre)1Tbo/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: epidermis	Present	Regionally restricted	2A middle	Reduced expression in the suprabasal layer.

2A right ©

Specimen 2A deltaep: embryonic day 17.5; Fosl2^tm2Wag/Fosl2^tm2Wag, Tg(KRT5-cre)1Tak/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: epidermis	Weak		2A right	Reduced expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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