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Gene Expression Data
Assay Details
Assay
Reference: J:85739 Rice R, et al., Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol. 2003 Oct 1;262(1):75-87
Assay type: RNA in situ
MGI Accession ID: MGI:6324513
Gene symbol: Msx2
Gene name: msh homeobox 2
Probe: pHOX8
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Widespread 4G Expression throughout calvarial osteogenic mesenchyme.

Specimen 4H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present 4H Expression throughout calvarial osteogenic mesenchyme.

Specimen 4I: embryonic day 13.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS21: head mesenchyme Present Regionally restricted 4I Expression restricted to lateral head mesenchyme. Expression limited to calvarial mesenchyme condensation and a region extending a short distance into osteogenic mesenchyme beyond condensation sites. No expression detected more superiorly in osteogenic mesenchyme.

Specimen 4J: embryonic day 13.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present 4J

Specimen 4K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: head mesenchyme Present Regionally restricted 4K Expression in periosteum.

Specimen 4L: embryonic day 15.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS23: head mesenchyme Present Regionally restricted 4L Expression further limited to periosteum of rudimentary bones.

Specimen mutant not shown: embryonic day 15.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS23: craniocervical region bone Present Authors report other craniofacial structures exhibited normal expression pattern in mutant tissue.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory