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Gene Expression Data
Assay Details
Assay
Reference: J:85739 Rice R, et al., Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol. 2003 Oct 1;262(1):75-87
Assay type: RNA in situ
MGI Accession ID: MGI:6324512
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe11
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4A Expression in osteogenic condensations.
Specimen 4B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4B Expression in osteogenic condensations.
Specimen 4C: embryonic day 13.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4C Expression pattern appeared normal in mutant at E13.
Specimen 4D: embryonic day 13.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Present Regionally restricted 4D Expression pattern appeared normal in mutant at E13.
Specimen 4E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4E Expression in preosteoblasts between brain and epidermis.
Specimen 4F: embryonic day 15.5; Foxc1ch/Foxc1ch (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4F Expression limited to initial condensation site - regions surrounding the rudimentary calvarial bone. No expression more superiorly in calvarial mesenchyme,.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory