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Gene Expression Data
Assay Details
Assay
Reference: J:85739 Rice R, et al., Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol. 2003 Oct 1;262(1):75-87
Assay type: RNA in situ
MGI Accession ID: MGI:6324508
Gene symbol: Foxc1
Gene name: forkhead box C1
Probe: Fkh1/Mf1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Present Regionally restricted 1A Some expression localized in calvarial mesenchyme.

Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: chondrocranium Strong 1B Intense expression in condensing prechondrogenic calvarial mesenchyme.
TS20: head mesenchyme Strong Regionally restricted 1B Intense expression in prechondrogenic condensations of developing cranial base and nasal cartilages.
TS20: meninges Strong 1B Strong expression in primitive meningeal layers.

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: chondrocranium pre-cartilage condensation Strong 1C Intense expression in condensing prechondrogenic calvarial mesenchyme.
TS21: head mesenchyme Strong Regionally restricted 1C Expression in calvarial mesenchyme between brain and surface ectoderm. Intense expression in precondrogenic condensations of developing cranial base and nasal cartilages.
TS21: frontal bone primordium Weak 1C Minimal expression in mesenchymal condensation of frontal bone.
TS21: meninges Present 1C Strong expression in primitive meningeal layers.

Specimen 1D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium bone Present Regionally restricted 1D Expression localized to osteoblasts and periosteum of calvarial bones.
TS23: meninges Present 1D

Specimen 1I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: parietal bone Absent 1I No expression in mesenchymal condensations of osteogenic fronts of parietal bone.
TS23: head mesenchyme Strong Regionally restricted 1I Strong expression in sutural mesenchyme.
TS23: perichondrium Present 1I Expression limited to perichondrium.

Specimen 1M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible Strong Regionally restricted 1M Strong expression in osteoblasts of mandible.
TS23: Meckel's cartilage Strong Regionally restricted 1M Strong expression in perichondrium of Meckel's cartilage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory