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Gene Expression Data
Assay Details
Assay
Reference: J:78344 Mustonen T, et al., Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Dev Biol. 2002 Aug 15;248(2):281-93
Assay type: RNA in situ
MGI Accession ID: MGI:6323252
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Probe: Hes1 probe16
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2M: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: oral epithelium Strong 2M
TS21: stellate reticulum Strong 2M
TS21: tooth epithelium Present Regionally restricted 2M Basal epithelial cells and enamel knot mostly negative for expression.
TS21: enamel knot Ambiguous 2M
TS21: tooth mesenchyme Strong Regionally restricted 2M Intense expression in condensed outer dental mesenchyme at early bud stage
Specimen 2N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: stellate reticulum Strong 2N
TS21: tooth epithelium Present Regionally restricted 2N Basal epithelial cells mostly negative for expression.
TS21: enamel knot Ambiguous 2N Enamel knot mostly negative for expression.
TS21: tooth mesenchyme Present Regionally restricted 2N Expression restricted to peripheral mesenchyme forming the dental follicle.
Specimen 2O: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: oral epithelium Strong 2O
TS22: stellate reticulum Strong 2O
TS22: tooth epithelium Present Regionally restricted 2O Basal epithelial cells mostly negative for expression.
TS22: enamel knot Ambiguous 2O Enamel knot mostly negative for expression.
TS22: tooth mesenchyme Present Regionally restricted 2O Expression restricted to peripheral mesenchyme forming the dental follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory