Gene Expression Data
Assay Details
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Assay
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Reference:
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J:78344
Mustonen T, et al., Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Dev Biol. 2002 Aug 15;248(2):281-93
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6323249
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Gene symbol:
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Jag1
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Gene name:
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jagged 1
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Probe:
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Ser-1 cDNA
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2G:
embryonic day 13.0
(more  )
Specimen
2G:
(close  )
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Genetic Background:
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NMRI
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: stellate reticulum |
Present |
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2G
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| TS21: tooth epithelium |
Present |
Regionally restricted |
2G
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Expression in stellate reticulum cells of epithelium. No expression in basal epithelial cells.
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| TS21: dental lamina |
Strong |
Regionally restricted |
2G
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Specifically intense expression in region of dental lamina connecting tooth germ to oral epithelium.
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| TS21: tooth mesenchyme |
Strong |
Widespread |
2G
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Intense expression in throughout condensed dental mesenchyme.
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Specimen
2H:
embryonic day 13.5
(more )
Specimen
2H:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: stellate reticulum |
Present |
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2H
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| TS21: tooth epithelium |
Present |
Regionally restricted |
2H
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Expression in stellate reticulum cells of epithelium. No expression in basal epithelial cells. Transient expression in enamel knot.
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| TS21: enamel knot |
Present |
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2H
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Transient expression in enamel knot.
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| TS21: dental lamina |
Strong |
Regionally restricted |
2H
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Specifically intense expression in region of dental lamina connecting tooth germ to oral epithelium.
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| TS21: tooth mesenchyme |
Present |
Regionally restricted |
2H
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Expression dowregulated in mesenchyme closest to epithelial bud forming the dental papilla. Expression maintained in periphery of dental mesenchyme forming dental follicle.
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Specimen
2I:
embryonic day 14.0
(more )
Specimen
2I:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools