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Gene Expression Data
Assay Details
Assay
Reference: J:32017 Offield MF, et al., PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6316656
Gene symbol: Slc2a2
Gene name: solute carrier family 2 (facilitated glucose transporter), member 2
Results
Specimen 6A: embryonic day 18.5; Pdx1tm2Cvw/Pdx1+ (more )
Note: Double labeled: brown - Glut2 (Slc2a2); blue - Ins1 (assay MGI:6316654 and Ins2 (assay MGI:6316655).
Structure Level Pattern Image Note
TS26: cystic duct Strong Regionally restricted 6A High levels of expression in epithelial lining of cystic duct.

Specimen 6B: embryonic day 18.5; Pdx1tm2Cvw/Pdx1+ (more )
Note: Double labeled: brown - Glut2 (Slc2a2); blue - Ins1 (assay MGI:6316654 and Ins2 (assay MGI:6316655).
Structure Level Pattern Image Note
TS26: pancreatic duct Present Regionally restricted 6B Authors report expression in villi on basolateral surfaces of columnar epithelium.

Specimen 6C: embryonic day 18.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Note: Double labeled: brown - Glut2 (Slc2a2); blue - Ins1 (assay MGI:6316654 and Ins2 (assay MGI:6316655).
Structure Level Pattern Image Note
TS26: pancreatic duct Strong Regionally restricted 6C Intense expression in dorsal ductule epithelium having a cuboidal morphology similar to that of the cystic duct. Reduced expression in numerous evaginations of ductules.
TS26: duodenum epithelium Strong Regionally restricted 6C Continuation of intense expression into aberrant cuboidal epihtelium of rostral-most duodenum.

Specimen 6D: embryonic day 18.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Note: Double labeled: brown - Glut2 (Slc2a2); blue - Ins1 (assay MGI:6316654 and Ins2 (assay MGI:6316655).
Structure Level Pattern Image Note
TS26: duodenum epithelium Strong Regionally restricted 6D More intense expression in abnormal duodenal epithelium than in the villi. Patches of reduced expression in cuboidal epithelium corresponding to regions of transition to normal columnar epithelium.

Specimen 6E: embryonic day 16.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Note: Double labeled: brown - Glut2 (Slc2a2); blue - Ins1 (assay MGI:6316654 and Ins2 (assay MGI:6316655).
Structure Level Pattern Image Note
TS24: pancreatic duct Present Regionally restricted 6E Expression in evaginations of dorsal ductule epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory