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Gene Expression Data
Assay Details
Assay
Reference: J:155247 Hierholzer A, et al., beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Dev Dyn. 2009 Aug 24;239(1):191-199
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6315577
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3C: embryonic day 8.5; Ctnnb1tm2.1Kem/Ctnnb1+, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: embryo ectoderm Present 3E , 3C Expression is at the membrane in cells of the three germ layers.
TS13: embryo endoderm Present 3E , 3C Expression is at the membrane in cells of the three germ layers.
TS13: embryo mesoderm Present 3E , 3C Expression is at the membrane in cells of the three germ layers.

Specimen 3D: embryonic day 8.5; Ctnnb1tm2.1Kem/Ctnnb1tm2.1Kem, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: embryo ectoderm Weak 3F , 3D Expression at the membrane in cells of the three germ layers is reduced in the posterior embryo.
TS13: embryo endoderm Weak 3F , 3D Expression at the membrane in cells of the three germ layers is reduced in the posterior embryo.
TS13: embryo mesoderm Weak 3F , 3D Expression at the membrane in cells of the three germ layers is reduced in the posterior embryo.

Specimen 7A: embryonic day 9.5; Ctnnb1tm2.1Kem/Ctnnb1+, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: hindgut diverticulum epithelium Present 7A
TS15: neural tube Present 7A

Specimen 7B: embryonic day 9.5; Ctnnb1tm2.1Kem/Ctnnb1tm2.1Kem, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: neural tube Weak 7B'' , 7B , 7B''' , 7B'
TS15: hindgut diverticulum epithelium Present 7B , 7B' , 7B''' Expression in this tissue is the same as in wild-type.
TS15: embryo Present Regionally restricted 7B Most cells in the posterior part of the embryo have lost expression.

Specimen 8D: embryonic day 10.5; Ctnnb1tm2.1Kem/Ctnnb1tm2.1Kem, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube Present 8D , 8D'

Specimen 8G: embryonic day 10.5; Ctnnb1tm2.1Kem/Ctnnb1tm2.1Kem, Tg(Cdx1-cre)23Kem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: surface ectoderm Present Regionally restricted 8G' , 8G Expression is absent in the posterior part of the embryo (shown).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory