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Gene Expression Data
Assay Details
Assay
Reference: J:91052 Cobourne MT, et al., Restriction of sonic hedgehog signalling during early tooth development. Development. 2004 Jun;131(12):2875-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6314686
Gene symbol: Shh
Gene name: sonic hedgehog
Antibody: anti-Shh (H-160; sc9024)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dental placode Present 3A Expressed throughout the epithelial thickenings of the future teeth.
TS19: jaw primordium mesenchyme Absent 3A
Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present 3C Expressed in an expanded region of bud epithelium.
TS20: jaw primordium mesenchyme Present Regionally restricted 3C Expressed in mesenchymal cells situated around the bud tip.
Specimen 3E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Strong Regionally restricted 3E Expressed in the outer regions.
TS21: jaw mesenchyme Strong Regionally restricted 3E Expressed in the mesenchyme surrounding the tooth bud epithelium.
Specimen 3G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Present 3G
TS22: inner enamel epithelium Present 3G
TS22: dental papilla Present 3G
Specimen 3N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Absent 3N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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