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Gene Expression Data
Assay Details
Assay
Reference: J:91052 Cobourne MT, et al., Restriction of sonic hedgehog signalling during early tooth development. Development. 2004 Jun;131(12):2875-85
Assay type: RNA in situ
MGI Accession ID: MGI:6314673
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA37
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dental placode Present 3B Expressed throughout the epithelial thickenings of the future teeth. Protein had a wider distribution in the epithelium.
TS19: jaw primordium mesenchyme Absent 3B
Specimen 3D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present Regionally restricted 3D Expressed only in a small group of epithelial cells situated at the tip of the tooth bud.
TS20: jaw primordium mesenchyme Absent 3D
Specimen 3F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present Regionally restricted 3F Expressed remained in a small group of epithelial cells situated at the tip of the tooth bud.
TS21: jaw mesenchyme Absent 3F
Specimen 3H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Strong 3H
TS22: dental papilla Absent 3H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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