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Gene Expression Data
Assay Details
Assay
Reference: J:248902 De Tomasi L, et al., Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice. Am J Hum Genet. 2017 Nov 2;101(5):803-814
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6307068
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesonephric tubule of male Present 4A upper
TS21: metanephros Present 4A upper
TS21: nephric duct of male Present 4A upper
TS21: paramesonephric duct of male Present 4A upper
TS21: ureter Present 4A upper
Specimen 4A +/-: embryonic day 13.5; Greb1lem1Cjea/Greb1l+ (more )
Structure Level Pattern Image Note
TS21: mesonephric tubule of male Present 4A middle
TS21: metanephros Present 4A middle
TS21: nephric duct of male Present 4A middle
TS21: paramesonephric duct of male Present 4A middle
TS21: ureter Present 4A middle A unilateral double ureter was seen.
Specimen 4A -/-: embryonic day 13.5; Greb1lem1Cjea/Greb1lem1Cjea (more )
Structure Level Pattern Image Note
TS21: metanephros Absent 4A lower Absence of kidney.
TS21: nephric duct of male Absent 4A lower Absence of Wolffian duct.
TS21: paramesonephric duct of male Absent 4A lower Absence of Mullerian duct.
TS21: mesonephric tubule of male Present 4A lower
TS21: ureter Present 4A lower Expressed in some structures that could be interpreted as a remnant of ureteric bud.
Specimen 4B +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesonephric tubule of female Present 4B upper
TS21: metanephros Present 4B upper
TS21: nephric duct of female Present 4B upper
TS21: paramesonephric duct of female Present 4B upper
TS21: ureter Present 4B upper
Specimen 4B +/-: embryonic day 13.5; Greb1lem1Cjea/Greb1l+ (more )
Structure Level Pattern Image Note
TS21: mesonephric tubule of female Present 4B middle
TS21: metanephros Present 4B middle
TS21: nephric duct of female Present 4B middle
TS21: paramesonephric duct of female Present 4B middle
TS21: ureter Present 4B middle
Specimen 4B -/-: embryonic day 13.5; Greb1lem1Cjea/Greb1lem1Cjea (more )
Structure Level Pattern Image Note
TS21: metanephros Absent 4B lower Absence of kidney.
TS21: nephric duct of female Absent 4B lower Absence of Wolffian duct.
TS21: paramesonephric duct of female Absent 4B lower Absence of Mullerian duct.
TS21: mesonephric tubule of female Present 4B lower
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory