Ptch1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:170964 Zhu J, et al., Analysis of mutants with altered shh activity and posterior digit loss supports a biphasic model for shh function as a morphogen and mitogen. Dev Dyn. 2011 May;240(5):1303-10
Assay type:	RNA in situ
MGI Accession ID:	MGI:6306940
Gene symbol:	Ptch1
Gene name:	patched 1

Probe:

Ptch1 probe19

Results

1A' ©

Specimen 1A': embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: forelimb bud	Present		1A'

1A'' ©

Specimen 1A'': embryonic day 9.75 (more

)

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Present		1A''

1A''' ©

Specimen 1A''': embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		1A'''

1B' ©

Specimen 1B': embryonic day 9.5; Wnt7a^tm1Amc/Wnt7a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS15: forelimb bud	Weak		1B'	Expression initially low.

1B'' ©

Specimen 1B'': embryonic day 9.75; Wnt7a^tm1Amc/Wnt7a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Present		1B''	Expression recovers rapidly to near normal levels.

1B''' ©

Specimen 1B''': embryonic day 10.5; Wnt7a^tm1Amc/Wnt7a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		1B'''	Expression at near normal levels.

1C' ©

Specimen 1C': embryonic day 9.5; Shh^tm2Amc/Shh^{tm1(EGFP/cre)Cjt} (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS15: forelimb bud	Present		1C'	Expression begins at near normal levels.

1C'' ©

Specimen 1C'': embryonic day 9.75; Shh^tm2Amc/Shh^{tm1(EGFP/cre)Cjt} (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Weak		1C''	Authors report expression declines.

1C''' ©

Specimen 1C''': embryonic day 10.5; Shh^tm2Amc/Shh^{tm1(EGFP/cre)Cjt} (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Weak		1C'''	Authors report expression declines.

1F' ©

Specimen 1F': embryonic day 9.5; Shh^tm2Amc/Shh^tm1Chg, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS15: forelimb bud	Absent		1F'

1F'' ©

Specimen 1F'': embryonic day 9.75; Shh^tm2Amc/Shh^tm1Chg, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS16: forelimb bud	Absent		1F''

1F''' ©

Specimen 1F''': embryonic day 10.5; Shh^tm2Amc/Shh^tm1Chg, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Absent		1F'''

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