Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:218850 Bisson JA, et al., Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT. Dev Biol. 2015 Feb 1;398(1):80-96
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6305281
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved caspase-3 (Asp175) (5A1E) (#9664)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

1A ©

Specimen 1A: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: outflow tract	Present	Regionally restricted	1A	Expression in walls of outflow tract and roof of outflow tract.
TS15: dorsal mesocardium	Present		1A
TS15: foregut epithelium	Present		1A	Expression in foregut endoderm

1C ©

Specimen 1C: embryonic day 9.5; Wnt11^tm1Amc/Wnt11^tm1Amc, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS15: outflow tract	Weak	Regionally restricted	1C	Reduced expression in walls of outflow tract and roof of outflow tract.
TS15: dorsal mesocardium	Weak	Regionally restricted	1C

1E ©

Specimen 1E: embryonic day 9.5; Wnt11^tm1Amc/Wnt11^tm1Amc, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS15: central nervous system	Strong	Regionally restricted	1E	Authors report expression in large numbers of cells within otic placodes and neural tube.
TS15: otic pit	Strong	Regionally restricted	1E	Authors report expression in large numbers of cells within otic placodes and neural tube.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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