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Gene Expression Data
Assay Details
Assay
Reference: J:188806 Hurd EA, et al., Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 2012 Sep;129(9-12):308-23
Assay type: RNA in situ
MGI Accession ID: MGI:6305270
Gene symbol: Msx1
Gene name: msh homeobox 1
Probe: Msx1 probe40
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 10F: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 10F Medial and lateral expression domains were detected.
Specimen 10L: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 10L Medial and lateral expression domains were preserved.
Specimen 10R: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 10R Medial expression was preserved, but the lateral expression domain was absent.
Specimen 10X: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 10X Medial expression was preserved, but the lateral expression domain was absent.
Specimen Table 1 +/+ E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 Gt/+ E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Absent
Specimen Table 1 Cond. het E11.5: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 CKO E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory