Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:55441
Weaver M, et al., Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development. 1999 Sep;126(18):4005-15
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:6296569
|
|
Gene symbol:
|
Bmp4
|
|
Gene name:
|
bone morphogenetic protein 4
|
|
Reporter:
|
lacZ
|
|
|
Direct Detection
|
|
|
Results
|
Specimen
1A:
embryonic day 9.0; Bmp4tm2Blh/Bmp4 +
(more )
Note: 19 somite-stage embryo.
Specimen
1A:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 9.0
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
19 somite-stage embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS14: trunk mesenchyme |
Present |
Regionally restricted |
1A
|
Expression is in two distinct domains in the ventral mesenchyme surrounding the gut tube and is slighly larger on the right side.
|
Specimen
1B:
embryonic day 9.5; Bmp4tm2Blh/Bmp4 +
(more )
Note: 23 somite-stage embryo.
Specimen
1B:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
23 somite-stage embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk mesenchyme |
Present |
Regionally restricted |
1B
|
Expression is in the ventral mesenchyme.
|
Specimen
1C:
embryonic day 9.5; Bmp4tm2Blh/Bmp4 +
(more )
Note: 27 somite-stage embryo.
Specimen
1C:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
27 somite-stage embryo.
|
Specimen
1D:
embryonic day 9.5; Bmp4tm2Blh/Bmp4 +
(more )
Note: 27 somite-stage embryo.
Specimen
1D:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
27 somite-stage embryo.
|
Specimen
1E:
embryonic day 10.0; Bmp4tm2Blh/Bmp4 +
(more )
Note: 30 somite-stage embryo.
Specimen
1E:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 10.0
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
30 somite-stage embryo.
|
Specimen
1F:
embryonic day 11.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
1F:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: lung mesenchyme |
Present |
|
1F
|
|
| TS19: embryo endoderm |
Present |
Regionally restricted |
1F
|
Expression is in endodermal tips of the lung and is stronger in the endoderm of the accessory lobe.
|
| TS19: lung |
Present |
Regionally restricted |
1F
|
Expression is in endodermal tips of the lung and is stronger in the endoderm of the accessory lobe.
|
Specimen
1G:
embryonic day 11.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
1G:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo endoderm |
Present |
Regionally restricted |
1G
|
Expression is in endodermal tips of the lung.
|
| TS19: lung |
Present |
Regionally restricted |
1G
|
Expression is in endodermal tips of the lung.
|
Specimen
1H:
embryonic day 14.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
1H:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: endoderm |
Present |
Regionally restricted |
1H
|
Expression is in endoderm of the distal lung buds.
|
| TS22: lung |
Present |
Regionally restricted |
1H
|
Expression is in endoderm of the distal lung buds.
|
Specimen
1I:
embryonic day 17.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
1I:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 17.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS25: endoderm |
Present |
Regionally restricted |
1I
|
Expression is in the highly ramified respiratory endoderm of the lung, particularly in endoderm at the periphery.
|
| TS25: lung |
Present |
Regionally restricted |
1I
|
Expression is in the highly ramified respiratory endoderm of the lung, particularly in endoderm at the periphery.
|
| TS25: lung mesenchyme |
Absent |
|
1I
|
|
Specimen
2C left:
embryonic day 11.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
2C left:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
not shown:
embryonic day 13.5; Bmp4tm2Blh/Bmp4 +
(more )
Specimen
not shown:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac
|
|
Mutant Allele(s):
|
Bmp4tm2Blh/Bmp4+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|