Gene Expression Data
Assay Details
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Assay
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Reference:
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J:56236
Dickman ED, et al., Abnormal skeletogenesis occurs coincident with increased apoptosis in the Splotch (Sp2H) mutant: putative roles for Pax3 and PDGFRalpha in rib patterning. Anat Rec. 1999 Jul 1;255(3):353-61
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6295972
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Gene symbol:
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Pax3
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Gene name:
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paired box 3
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Results
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Specimen
2a:
embryonic day 10.5
(more )
Specimen
2a:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2b:
(close )
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Genetic Background:
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involves: 101 * C3H/He
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Mutant Allele(s):
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Pax3Sp-2H/Pax3Sp-2H
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: trunk somite |
Weak |
Regionally restricted |
2b
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Expression was decreased in the thoracic somites. Expression in somites in the posterior region of the embryo showed relatively normal expression.
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| TS16: cardiac neural crest |
Absent |
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2b
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| TS16: limb |
Absent |
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2b
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| TS16: neural tube |
Present |
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2b
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Expression in neural tube appeared to be unaffected in the mutant compared to wild type.
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Specimen
2d:
embryonic day 9.5
(more )
Specimen
2d:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Specimen
2e:
(close )
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Genetic Background:
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involves: 101 * C3H/He
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Mutant Allele(s):
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Pax3Sp-2H/Pax3Sp-2H
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk dermomyotome |
Present |
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2e
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At E9.5 normal expression was detected in the dermomyotome in the mutant.
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Specimen
2f:
embryonic day 10.5
(more )
Specimen
2f:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Specimen
2g:
(close )
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Genetic Background:
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involves: 101 * C3H/He
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Mutant Allele(s):
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Pax3Sp-2H/Pax3Sp-2H
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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