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Gene Expression Data
Assay Details
Assay
Reference: J:56236 Dickman ED, et al., Abnormal skeletogenesis occurs coincident with increased apoptosis in the Splotch (Sp2H) mutant: putative roles for Pax3 and PDGFRalpha in rib patterning. Anat Rec. 1999 Jul 1;255(3):353-61
Assay type: RNA in situ
MGI Accession ID: MGI:6295972
Gene symbol: Pax3
Gene name: paired box 3
Probe: Pax3 probe2
Probe preparation: Antisense RNA
Results
Specimen 2a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: trunk somite Present 2a
TS16: cardiac neural crest Present 2a
TS16: limb Present 2a
TS16: neural tube Present 2a

Specimen 2b: embryonic day 10.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS16: trunk somite Weak Regionally restricted 2b Expression was decreased in the thoracic somites. Expression in somites in the posterior region of the embryo showed relatively normal expression.
TS16: cardiac neural crest Absent 2b
TS16: limb Absent 2b
TS16: neural tube Present 2b Expression in neural tube appeared to be unaffected in the mutant compared to wild type.

Specimen 2d: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trunk dermomyotome Present 2d

Specimen 2e: embryonic day 9.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS15: trunk dermomyotome Present 2e At E9.5 normal expression was detected in the dermomyotome in the mutant.

Specimen 2f: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: limb Present 2f
TS16: trunk dermomyotome Present 2f

Specimen 2g: embryonic day 10.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS16: trunk dermomyotome Weak 2g By E10.5, Splotch mutants display a decrease in expression in the dermomyotome.
TS16: limb Absent 2g


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory