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Gene Expression Data
Assay Details
Assay
Reference: J:199592 Yang L, et al., ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates. Dev Biol. 2013 Aug 1;380(1):99-110
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6294700
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Antibody: anti-collagen X
Detection system: Cy3
Results
Specimen 4a WT E15.5 Proximal humerus: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 4a Anti-type X WT Proximal humerus Expression limited to hypertrophic zone.
Specimen 4a CKO/CKO E15.5 Proximal humerus: embryonic day 15.5; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 4a Anti-type X CKO/CKO Proximal humerus Minimal difference in chondrocyte hypertophy between wild-type and mutant embryos.
Specimen 4a WT E15.5 Distal femur: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: femur Present Regionally restricted 4a Anti-type X WT Distal femur Expression limited to hypertrophic zone.
Specimen 4a CKO/CKO E15.5 Distal femur: embryonic day 15.5; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: femur Present Regionally restricted 4a Anti-type X CKO/CKO Distal femur Minimal difference in chondrocyte hypertophy between wild-type and mutant embryos.
Specimen 4a WT E15.5 Proximal tibia: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 4a Anti-type X WT Proximal tibia Expression limited to hypertrophic zone.
Specimen 4a CKO/CKO E15.5 Proximal tibia: embryonic day 15.5; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 4a Anti-type X CKO/CKO Proximal tibia Minimal difference in chondrocyte hypertophy between wild-type and mutant embryos.
Specimen 4b WT newborn Proximal humerus: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 4b Anti-type X WT Proximal humerus Expression limited to hypertrophic zone.
Specimen 4b CKO/CKO newborn Proximal humerus: postnatal newborn; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 4b Anti-type X CKO/CKO Proximal humerus Diffuse expression throughout growth plate.
Specimen 4b WT newborn Distal femur: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: femur Present Regionally restricted 4b Anti-type X WT Distal femur Expression limited to hypertrophic zone.
Specimen 4b CKO/CKO newborn Distal femur: postnatal newborn; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: femur Present 4b Anti-type X CKO/CKO Distal femur Diffuse expression throughout growth plate.
Specimen 4b WT newborn Proximal tibia: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 4b Anti-type X WT Proximal tibia Expression limited to hypertrophic zone.
Specimen 4b CKO/CKO newborn Proximal tibia: postnatal newborn; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 4b Anti-type X CKO/CKO Proximal tibia Diffuse expression throughout growth plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory