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Gene Expression Data
Assay Details
Assay
Reference: J:197928 Soshnikova N, et al., Duplications of hox gene clusters and the emergence of vertebrates. Dev Biol. 2013 Jun 15;378(2):194-9
Assay type: RNA in situ
MGI Accession ID: MGI:6294441
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: Col2a1 probe17
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 3i: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present 3i

Specimen 3j: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present Regionally restricted 3j Authors report missing digit 1.

Specimen 3k: embryonic day 12.5; Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present Regionally restricted 3k

Specimen 3l: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu, Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present Regionally restricted 3l Authors report reduced numbers of presumtpive digits and mirror-image symmetrical digit pattern.

Specimen S3a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present S3a

Specimen S3b: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu, Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: hand pre-cartilage condensation Present S3b Authors report a hypoplastic limb.

Specimen S3c: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu, Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: forelimb Present S3c Authors report a hypoplastic limb.

Specimen S3d: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu, Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: forelimb Present S3d Authors report handplate was completely absent.

Specimen S3e: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot pre-cartilage condensation Present S3e

Specimen S3f: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu (more )
Structure Level Pattern Image Note
TS20: foot pre-cartilage condensation Present S3f

Specimen S3g: embryonic day 12.5; Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: foot pre-cartilage condensation Present S3g

Specimen S3h: embryonic day 12.5; Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu, Hoxctm1Nogu/Hoxctm1Nogu (more )
Structure Level Pattern Image Note
TS20: foot pre-cartilage condensation Present S3h


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory