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Gene Expression Data
Assay Details
Assay
Reference: J:28253 Tureckova J, et al., Comparison of expression of the msx-1, msx-2, BMP-2 and BMP-4 genes in the mouse upper diastemal and molar tooth primordia. Int J Dev Biol. 1995 Jun;39(3):459-68
Assay type: RNA in situ
MGI Accession ID: MGI:6286411
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA17
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A/B: embryonic day 11.0 (more )
Note: Embryonic age is 10 days and 20 hours.
Structure Level Pattern Image Note
TS18: 1st branchial arch maxillary component ectoderm Present 4A/B
TS18: 1st branchial arch maxillary component mesenchyme Present Regionally restricted 4A/B Expression is above the site of the prospective diastemal dental lamina and extends to the face epithelium.

Specimen 4C/D: embryonic day 12.0 (more )
Note: Embryonic age is 11 days and 20 hours.
Structure Level Pattern Image Note
TS20: mandibular process Present Regionally restricted 4C/D Expression is at the presumptive site of the distal part of the prospective diastemal dental lamina.
TS20: maxillary process epithelium Present Regionally restricted 4C/D Expression is at the presumptive site of the distal part of the prospective diastemal dental lamina.
TS20: mandibular process mesenchyme Present Regionally restricted 4C/D Expression is above the second and third diastemal dental primordia and proceeds buccally into the upper lip and distally into the molar region.
TS20: upper lip Present Regionally restricted 4C/D Expression is above the second and third diastemal dental primordia and proceeds buccally into the upper lip and distally into the molar region.

Specimen 4E/F: embryonic day 12.0 (more )
Note: Embryonic age is 11 days and 20 hours.
Structure Level Pattern Image Note
TS20: maxillary process mesenchyme Present Regionally restricted 4E/F Expression is above the second and third diastemal dental primordia and proceeds buccally into the upper lip and distally into the molar region.
TS20: maxillary process Present Regionally restricted 4E/F Expression is in the mesial part of the molar anlage extending palatally in a distal course.

Specimen 4G/H: embryonic day 12.5 (more )
Note: Embryonic age is 12 days and 8 hours.
Structure Level Pattern Image Note
TS20: maxillary process epithelium Present Regionally restricted 4G/H There is diffuse expression at the second and third diastemal dental primordia.
TS20: maxillary process mesenchyme Present Regionally restricted 4G/H Expression is above the second and third diastemal dental primordia and proceeds buccally into the upper lip and distally into the molar region.

Specimen 5A/B: embryonic day 12.5 (more )
Note: Embryonic age is 12 days and 8 hours.
Structure Level Pattern Image Note
TS20: maxillary process mesenchyme Present Regionally restricted 5A/B Expression is above the second and third diastemal dental primordia and proceeds buccally into the upper lip and distally into the molar region.
TS20: maxillary process Present Regionally restricted 5A/B Expression is in the mesial part of the molar anlage extending palatally in a distal course.
TS20: oral epithelium Present Regionally restricted 5A/B Expression is on the lingual side.

Specimen 5C/D: embryonic day 13.0 (more )
Note: Embryonic age is 12 days and 20 hours.
Structure Level Pattern Image Note
TS21: oral epithelium Present Regionally restricted 5C/D Expression is concentrated in the central superficial flat cells in the distal part of the second diastemal dental primordia and into the mesial part of the third diastemal dental primordia.

Specimen 5E/F: embryonic day 13.0 (more )
Note: Embryonic age is 12 days and 20 hours.
Structure Level Pattern Image Note
TS21: oral epithelium Present Regionally restricted 5E/F Expression is concentrated in the central flat cells in the distal part of the second diastemal dental primordia and into the mesial part of the third diastemal dental primordia.
TS21: molar epithelium Absent 5E/F

Specimen 5G/H: embryonic day 13.5 (more )
Note: Embryonic age is 12 days and 20 hours.
Structure Level Pattern Image Note
TS21: upper jaw molar epithelium Present Regionally restricted 5G/H Expression is in the middle of the convexity of the epithelial bud.
TS21: oral epithelium Absent 5G/H

Specimen not shown 13(8): embryonic day 13.5 (more )
Note: Embryonic age is 13 days and 8 hours.
Structure Level Pattern Image Note
TS21: upper jaw mesenchyme Present Regionally restricted Expression is surrounding the molar epithelial anlage and extends as far as the isthmus faucium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory