About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:41061 Zannini M, et al., TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J. 1997 Jun 2;16(11):3185-97
Assay type: RNA in situ
MGI Accession ID: MGI:6281325
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: TTF-1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Transcripts were hydrolyzed by alkaline hydrolysis to an average length of 150 nucleotides.
Results
Specimen 6A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present Regionally restricted 6A' , 6A Expression is in a small group of cells in the deep midline of the floor.
Specimen 6B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: thyroid primordium Absent 6B' , 6B
Specimen 6C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: thyroid primordium Present 6C
Specimen 6D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: thyroid primordium Present 6D
Specimen 6E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: thyroid gland Present 6E
Specimen 7A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future neurohypophysis Present 7A
Specimen 7B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future neurohypophysis Present 7B
Specimen 7C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future neurohypophysis Present 7C
Specimen 7D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future neurohypophysis Present 7D
Specimen 7E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neurohypophysis infundibulum Strong 7E
Specimen 8A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: thyroid gland Strong 8A
Specimen 8B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: thyroid gland Strong 8B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory