Gene Expression Data
Assay Details
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Assay
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Reference:
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J:194083
De Castro SC, et al., Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice. PLoS Genet. 2012;8(11):e1003059
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6276652
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Gene symbol:
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Lmnb1
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Gene name:
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lamin B1
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Probe:
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Lamin B1 probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1G:
embryonic day 10.5
(more  )
Specimen
1G:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
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1G
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Authors state the distribution of expression is comparable in wild type and mutant embryos.
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Specimen
1H:
(close )
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Genetic Background:
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involves: GFF
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Mutant Allele(s):
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Grhl3ct/Grhl3ct
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
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1H
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Authors state the distribution of expression is comparable in wild type and mutant embryos.
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Specimen
S1A:
embryonic day 10.5
(more )
Specimen
S1A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Strong |
Regionally restricted |
S1A
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Intense expression throughout most of the embryo, with the exception of the heart and dorsal surface.
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Specimen
S1C:
embryonic day 10.5
(more )
Specimen
S1C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: heart |
Ambiguous |
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S1C
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Authors report diminished or absent expression in the heart.
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Specimen
S1D:
embryonic day 10.5
(more )
Specimen
S1D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Present |
Regionally restricted |
S1D
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Authors report lack of expression in dorsal neural tube and surface ectoderm.
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| TS17: surface ectoderm |
Ambiguous |
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S1D
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Authors report lack of expression in dorsal neural tube and surface ectoderm.
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Specimen
S1E:
(close )
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Genetic Background:
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involves: GFF
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Mutant Allele(s):
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Grhl3ct/Grhl3ct
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Strong |
Regionally restricted |
S1E
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Intense expression throughout most of the embryo, with the exception of the heart and dorsal surface.
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Specimen
S1F:
embryonic day 10.5
(more )
Specimen
S1F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: heart |
Ambiguous |
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S1F
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Authors report diminished or absent expression in the heart.
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Specimen
S1G:
(close )
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Genetic Background:
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involves: GFF
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Mutant Allele(s):
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Grhl3ct/Grhl3ct
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: heart |
Ambiguous |
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S1G
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Authors report diminished or absent expression in the heart.
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Specimen
S1H:
(close )
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Genetic Background:
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involves: GFF
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Mutant Allele(s):
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Grhl3ct/Grhl3ct
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: heart |
Ambiguous |
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S1H
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Authors report diminished or absent expression in the heart.
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Specimen
S1I:
(close )
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Genetic Background:
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involves: GFF
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Mutant Allele(s):
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Grhl3ct/Grhl3ct
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Present |
Regionally restricted |
S1I
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Authors report lack of expression in dorsal neural tube and surface ectoderm, particularly evident in posterior neuropore region.
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| TS17: surface ectoderm |
Ambiguous |
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S1I
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Authors report lack of expression in dorsal neural tube and surface ectoderm, particularly evident in posterior neuropore region.
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