Gene Expression Data
Assay Details
Assay
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Reference:
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J:173124
Aujla PK, et al., The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary. Dev Biol. 2011 May 1;353(1):61-71
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6275016
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Gene symbol:
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Avp
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Gene name:
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arginine vasopressin
|
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Results
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Specimen
2A:
embryonic day 16.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
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Formaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: hypothalamus |
Present |
Regionally restricted |
2A
|
At level of the posterior lobe of pituitary, no expression in cell bodies in the region posterior to the supraoptic nucleus.
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Specimen
2B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
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Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
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Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: hypothalamus |
Present |
Regionally restricted |
2B
|
At level of the posterior lobe, expression in cells in a ventromedial cluster, as well as a few scattered cells laterally.
|
Specimen
2C:
embryonic day 16.5
(more )
Specimen
2C:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: hypothalamus |
Present |
Regionally restricted |
2C
|
At level of the medial median eminence, anterior to the posterior lobe, expression in medial cell bodies in a ventromedial cluster, medial to the supraoptic nucleus.
|
TS24: supraoptic nucleus |
Present |
Regionally restricted |
2C
|
Expression in a cluster superior to the optic nerve in the supraoptic nucleus.
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Specimen
2D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: median eminence |
Present |
Regionally restricted |
2D
|
Expression in more dorsal cells at the medial median eminence, anterior to the posterior lobe.
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TS24: hypothalamus |
Present |
Regionally restricted |
2D
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Expression in scattered cells medial to the supraoptic nucleus.
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Specimen
2G:
embryonic day 16.5
(more )
Specimen
2G:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: median eminence |
Present |
Regionally restricted |
2G
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Expression in the paraventricular nucleus, forming a trapezoid pattern at the third ventricle.
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Specimen
2I:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Specimen
3A:
embryonic day 18.5
(more )
Specimen
3A:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: paraventricular hypothalamic nucleus |
Strong |
Regionally restricted |
3A
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Robust expression within the paraventricular nucleus in a distinct pattern on either side of the third ventricle.
|
Specimen
3B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Specimen
3C:
embryonic day 18.5
(more )
Specimen
3C:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: supraoptic nucleus |
Present |
Regionally restricted |
3C
|
Expression in tight cluster of neurons superior to the optic nerve,
|
Specimen
3D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: supraoptic nucleus |
Present |
Diffuse |
3D
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More diffuse pattern of expression in the superior optic nucleus. Expression in neurons follow border of mesenchyme.
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Specimen
4A:
embryonic day 18.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Specimen
4B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Specimen
4C:
embryonic day 18.5
(more )
Specimen
4C:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: median eminence |
Present |
Regionally restricted |
4C
|
Expression in axons in the median eminence.
|
Specimen
4D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: median eminence |
Weak |
Regionally restricted |
4D
|
Decreased expression within the median eminence.
|
TS26: hypothalamus |
Present |
Regionally restricted |
4D
|
Expression in an ectopic cluster of cells lateral to the median eminence.
|
Specimen
5A:
embryonic day 18.5
(more )
Specimen
5A:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: supraoptic nucleus |
Present |
Regionally restricted |
5A
|
Expression in the supraoptic nucleus at the level of the anterior lobe in a cluster superior to the optic nerve
|
Specimen
5B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: median eminence |
Present |
Regionally restricted |
5B
|
At the level of a smaller anterior lobe, expression in axons traveling through the median eminence
|
TS26: supraoptic nucleus |
Present |
Regionally restricted |
5B
|
Expression in a cluster of neurons superior to the optic nerve in the supraoptic nucleus.
|
Specimen
5C:
embryonic day 18.5
(more )
Specimen
5C:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: supraoptic nucleus |
Present |
Regionally restricted |
5C
|
Expression in neurons in the supraoptic nucleus.
|
Specimen
5D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: median eminence |
Weak |
Regionally restricted |
5D
|
Decreased expression within the median eminence.
|
TS26: hypothalamus |
Present |
Regionally restricted |
5D
|
Expression in an ectopic cluster of cells lateral to the median eminence.
|
Specimen
5E:
embryonic day 18.5
(more )
Specimen
5E:
(close )
Genetic Background:
|
involves: C57BL/6J * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5F/F':
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
Mutant Allele(s):
|
Hes1tm1Fgu/Hes1tm1Fgu
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: median eminence |
Present |
Regionally restricted |
5F
,
5F'
|
At the level of the posterior lobe, no expression in axons traveling through the medial eminence.
|
TS26: supraoptic nucleus |
Weak |
Regionally restricted |
5F
,
5F'
|
Decreased expression within the median eminence.
|
TS26: hypothalamus |
Present |
Regionally restricted |
5F
,
5F'
|
Expression in an ectopic cluster of cells lateral to the median eminence.
|
|