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Gene Expression Data
Assay Details
Assay
Reference: J:154906 Wang W, et al., Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53
Assay type: RNA in situ
MGI Accession ID: MGI:6273223
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: alpha1(II) Collagen cDNA1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 5Aj: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present 5Aj

Specimen 5Aj': embryonic day 14.5; Atf4tm1Tow/Atf4tm1Tow (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Regionally restricted 5Aj' Authors state expression level was unchanged in Atf4-/- growth plates. Zone of expressing chondrocytes was shorter in Atf4-/- long bones.

Specimen 5Ak: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: humerus Present 5Ak

Specimen 5Ak': embryonic day 16.5; Atf4tm1Tow/Atf4tm1Tow (more )
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 5Ak' Authors state expression level was unchanged in Atf4-/- growth plates. Zone of expressing chondrocytes was shorter in Atf4-/- long bones.

Specimen 5Al: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: humerus Present 5Al

Specimen 5Al': postnatal day 0; Atf4tm1Tow/Atf4tm1Tow (more )
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 5Al' Authors state expression level was unchanged in Atf4-/- growth plates. Zone of expressing chondrocytes was shorter in Atf4-/- long bones.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory