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Gene Expression Data
Assay Details
Assay
Reference: J:163483 He G, et al., Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base. Dev Biol. 2010 Aug 15;344(2):720-30
Assay type: RNA in situ
MGI Accession ID: MGI:6268340
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: ColX probe3
Probe preparation: Antisense RNA
Results
Specimen 2E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: chondrocranium cartilage condensation Present Regionally restricted 2E Expression in presphenoid precursor.

Specimen 2F: embryonic day 16.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS24: chondrocranium cartilage condensation Present Regionally restricted 2F Wider region of expression in mutant presphenoid precursor.

Specimen E14.5 wild-type not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basioccipital cartilage condensation Present Expression in basiooccipital precursor in posterior cranial base.
TS22: chondrocranium cartilage condensation Present Regionally restricted No expression in wild-type or mutant presphenoid precursor.

Specimen E14.5 mutant not shown: embryonic day 14.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS22: basioccipital cartilage condensation Present Expression in basiooccipital precursor in posterior cranial base.
TS22: chondrocranium cartilage condensation Present Regionally restricted No expression in wild-type or mutant presphenoid precursor.

Specimen 4M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4M Expression in presphenoid bone precursor

Specimen 4N: embryonic day 15.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS23: chondrocranium cartilage condensation Present Regionally restricted 4N Expression domain slightly larger in area in mutant as compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory