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Gene Expression Data
Assay Details
Assay
Reference: J:160266 van Bueren KL, et al., Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome. Dev Biol. 2010 Apr 15;340(2):369-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6267474
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 4C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 3rd arch artery Strong Regionally restricted 4C Strong expression surrounding 3rd, 4th and 6th pharyngeal arch arteries.
TS19: 4th arch artery Strong Regionally restricted 4C Strong expression surrounding 3rd, 4th and 6th pharyngeal arch arteries.
TS19: 6th arch artery Strong Regionally restricted 4C Strong expression surrounding 3rd, 4th and 6th pharyngeal arch arteries.

Specimen 4D: embryonic day 11.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS19: 3rd arch artery Absent 4D Authors state expression surrounding pharyngeal arch arteries is lost or diminished in mutant embryos.
TS19: 6th arch artery Weak 4D Authors state expression surrounding pharyngeal arch arteries is lost or diminished in mutant embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory