Fgf3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:87221 Alvarez Y, et al., Requirements for FGF3 and FGF10 during inner ear formation. Development. 2003 Dec;130(25):6329-38
Assay type:	RNA in situ
MGI Accession ID:	MGI:6259812
Gene symbol:	Fgf3
Gene name:	fibroblast growth factor 3

Probe:	Fgf3 probe27
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

1D +/+ ©

Specimen 1D +/+: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: future hindbrain	Present		1D +/+

1D -/- ©

Specimen 1D -/-: embryonic day 8.5; Fgf3^tm1Sng/Fgf3^tm1Sng (more

)

Structure	Level	Pattern	Image	Note
TS13: embryo	Absent		1D -/-

4A ©

Specimen 4A: embryonic day 8.0 (more

)

Structure	Level	Pattern	Image	Note
TS12: future hindbrain	Present	Regionally restricted	4A	Broad domain of expression in neurectoderm extending from midbrain-hindbrain boundary to rhombomere 6.
TS12: rhombomere	Strong	Regionally restricted	4A	Highest levels of expression in rhombomeres 4, 5 and 6 next to developing otic placode.

4B ©

Specimen 4B: embryonic day 9.0 (more

)

Structure	Level	Image	Note
TS14: rhombomere 5	Strong	4B	Expression concentrated in rhombomeres 5 and 6.
TS14: rhombomere 6	Strong	4B	Expression concentrated in rhombomeres 5 and 6.
TS14: otic placode	Present	4B

4C ©

Specimen 4C: embryonic day 9.0 (more

)

Structure	Level	Pattern	Image	Note
TS14: rhombomere 5	Strong		4C
TS14: otic placode	Present		4C

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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