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Gene Expression Data
Assay Details
Assay
Reference: J:262090 Nagata K, et al., ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis. Acta Neuropathol. 2016 Jul;132(1):111-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6259587
Gene symbol: Isl2
Gene name: insulin related protein 2 (islet 2)
Antibody: anti-Isl1/2
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen S1a/c: embryonic day 9.5 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Ecel1 (assay MGI:6259588).
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted S1a , S1c Expressed in the motoneurons in the ventral spinal cord.
Specimen S1d/f: embryonic day 10.0 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Ecel1 (assay MGI:6259588).
Structure Level Pattern Image Note
TS16: neural tube lateral wall Present Regionally restricted S1d , S1f Expressed in the motoneurons in the ventral spinal cord.
TS16: dorsal root ganglion Present S1f , S1d
Specimen S1g/i: embryonic day 10.5 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Ecel1 (assay MGI:6259588).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S1i , S1g Expressed in the motoneurons in the ventral spinal cord.
TS17: dorsal root ganglion Present S1g , S1i
Specimen S1j/l: embryonic day 12.5 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Ecel1 (assay MGI:6259588).
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Present Regionally restricted S1l , S1j Expressed in the motoneurons in the ventral spinal cord.
TS20: dorsal root ganglion Present S1j , S1l
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory