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Gene Expression Data
Assay Details
Assay
Reference: J:264553 Tarchini B, et al., A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development. Dev Biol. 2018 Nov 15;443(2):153-164
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6258748
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 3B +/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1+ (more )
Note: Triple labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747); blue - DAPI.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 3B +/dwnd upper Expression in prosensory domain.
Specimen 3B dwnd/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1dwnd (more )
Note: Triple labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747); blue - DAPI.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 3B dwnd/dwnd upper Authors report expression in cochlear floor in homozygote comparable to heterozygote control.
Specimen 3C +/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1+ (more )
Note: Double labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747).
Structure Level Pattern Image Note
TS24: retina Present 3C +/dwnd upper
Specimen 3C dwnd/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1dwnd (more )
Note: Double labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747).
Structure Level Pattern Image Note
TS24: retina Present 3C dwnd/dwnd upper
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory