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Gene Expression Data
Assay Details
Assay
Reference: J:31081 Wilson DB, et al., Alterations in cranial morphogenesis in the Lp mutant mouse. J Craniofac Genet Dev Biol. 1995 Oct-Dec;15(4):182-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6258396
Gene symbol: Ncam1
Gene name: neural cell adhesion molecule 1
Antibody: Anti-NCAM
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1F: embryonic day 10.5 (more )
Note: This 'normal' specimen was either +/+ or Lp/+.
Structure Level Pattern Image Note
TS17: hindbrain roof plate Present 1F

Specimen 1G: embryonic day 10.5 (more )
Note: This 'normal' specimen was either +/+ or Lp/+.
Structure Level Pattern Image Note
TS17: notochord Present 1G
TS17: head mesenchyme Ambiguous Regionally restricted 1G The mesenchyme surrounding the neuroepithelium was poorly labeled.

Specimen 2F: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2F In the mutant, expression was detected in the everted tip of the open neural fold.

Specimen 2G: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: notochord Present 2G Expression is similar to normal in the mutant.
TS17: head mesenchyme Ambiguous 2G The mesenchyme surrounding the neuroepithelium was poorly labeled. Expression is similar to normal in the mutant.

Specimen 3C: embryonic day 11.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS19: hindbrain Present 3C In the mutant, expression was similar to normal.

Specimen 3D: embryonic day 11.5 (more )
Note: This 'normal' specimen was either +/+ or Lp/+.
Structure Level Pattern Image Note
TS19: hindbrain Present 3D

Specimen 4E: embryonic day 12.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 4E Expression was detected in the distal tips of the abnormal hindbrain.

Specimen 4F: embryonic day 12.5 (more )
Note: This 'normal' specimen was either +/+ or Lp/+.
Structure Level Pattern Image Note
TS20: hindbrain roof Present 4F

Specimen 6A: embryonic day 12.5 (more )
Note: This 'normal' specimen was either +/+ or Lp/+.
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 6A Expression was detected in the notochord, but the surrounding sheath was negative.

Specimen 6B: embryonic day 12.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 6B As in the normal embryo, expression was detected in the notochord of the abnormal embryo, but the surrounding sheath was negative.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory