About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:260421 Mesman S, et al., Expression analyzes of early factors in midbrain differentiation programs. Gene Expr Patterns. 2018 Jan;27:8-15
Assay type: RNA in situ
MGI Accession ID: MGI:6258328
Gene symbol: Neurod1
Gene name: neurogenic differentiation 1
Probe: Neurod1 probe9
Probe preparation: labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen 3A E11.5 Lateral: embryonic day 11.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS19: midbrain Present 3A E11.5 Lateral Specific expression in midbrain area at E11.5.
TS19: prosomere 1 Present 3A E11.5 Lateral Expression into the prosomere 3 area.
TS19: prosomere 2 Present 3A E11.5 Lateral Expression into the prosomere 3 area.
TS19: prosomere 3 Present 3A E11.5 Lateral Expression into the prosomere 3 area.

Specimen 3A E11.5 Medial: embryonic day 11.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS19: midbrain Present 3A E11.5 Medial Specific expression in midbrain area at E11.5.
TS19: prosomere 1 Present 3A E11.5 Medial Expression into the prosomere 3 area.
TS19: prosomere 2 Present 3A E11.5 Medial Expression into the prosomere 3 area.
TS19: prosomere 3 Present 3A E11.5 Medial Expression into the prosomere 3 area.

Specimen 3A E12.5 Lateral: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain Present 3A E12.5 Lateral Specific expression in midbrain area.
TS20: prosomere 1 Strong 3A E12.5 Lateral Expression into the prosomere 3 area.
TS20: prosomere 2 Strong 3A E12.5 Lateral Expression into the prosomere 3 area.
TS20: prosomere 3 Strong 3A E12.5 Lateral Expression into the prosomere 3 area.

Specimen 3A E12.5 Medial: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain Present 3A E12.5 Medial Specific expression in midbrain area.
TS20: prosomere 1 Present 3A E12.5 Medial Expression into the prosomere 3 area.
TS20: prosomere 2 Present 3A E12.5 Medial Expression into the prosomere 3 area.
TS20: prosomere 3 Present 3A E12.5 Medial Expression into the prosomere 3 area.

Specimen 3A1: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 3A1 Expression overlaps with caudal part of Th-expressing neuronal population in midbrain.

Specimen 3A E14.5 Lateral: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: midbrain Ambiguous 3A E14.5 Lateral

Specimen 3A E14.5 Medial: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: prosomere 2 Present Regionally restricted 3A E14.5 Medial Expression overlaps with Th-expressing neurons in rostral part of mdDA (mesodiencephalic dopaminergic) area in prosomeres 2 and 3.
TS22: prosomere 3 Present Regionally restricted 3A E14.5 Medial Expression overlaps with Th-expressing neurons in rostral part of mdDA (mesodiencephalic dopaminergic) area in prosomeres 2 and 3.

Specimen 3A2: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: prosomere 2 Present Regionally restricted 3A2 Expression overlaps with Th-expressing neurons in rostral part of mdDA (mesodiencephalic dopaminergic) area in prosomeres 2 and 3.
TS22: prosomere 3 Present Regionally restricted 3A2 Expression overlaps with Th-expressing neurons in rostral part of mdDA (mesodiencephalic dopaminergic) area in prosomeres 2 and 3.

Specimen 3B E11.5 Rostral: embryonic day 11.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS19: midbrain floor plate Present Regionally restricted 3B E11.5 Rostral Expression mainly in subventricular zone of floor plate and basal plate of midbrain.

Specimen 3B E11.5 Caudal: embryonic day 11.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS19: midbrain mantle layer Present Regionally restricted 3B E11.5 Caudal Expression mainly in subventricular zone of floor plate and basal plate of midbrain.

Specimen 3B E12.5 Rostral: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain floor plate Present Regionally restricted 3B E12.5 Rostral Expression overlaps with rostral part of Th-expressing neuronal population.

Specimen 3B E12.5 Caudal: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain floor plate Present Regionally restricted 3B E12.5 Caudal Expression overlaps with rostral part of Th-expressing neuronal population.

Specimen 3B1: embryonic day 12.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS20: midbrain floor plate Present Regionally restricted 3B1 Expression overlaps with rostral part of Th-expressing neuronal population.

Specimen 3B E14.5 Rostral: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present Regionally restricted 3B E14.5 Rostral Expression in midbrain subventricular zone, just below the ventricular zone, overlapping Th-expressing neuronal population.

Specimen 3B E14.5 Caudal: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present Regionally restricted 3B E14.5 Caudal Expression in midbrain subventricular zone, just below the ventricular zone, overlapping Th-expressing neuronal population.

Specimen 3B2: embryonic day 14.5 (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present Regionally restricted 3B2 Expression in midbrain subventricular zone, just below the ventricular zone, overlapping Th-expressing neuronal population.

Specimen 3B Adult: postnatal adult (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS28: substantia nigra Weak 3B Adult Weak expression in neurons that are part of the substantia nigra.

Specimen 3B3: postnatal adult (more )
Note: Double labeled: blue - Neurod1; brown - Th (assay MGI:6258336).
Structure Level Pattern Image Note
TS28: substantia nigra Weak 3B3 Weak expression in neurons that are part of the substantia nigra.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory