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Gene Expression Data
Assay Details
Assay
Reference: J:260416 Kibe K, et al., Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105
Assay type: RNA in situ
MGI Accession ID: MGI:6257002
Gene symbol: Hey2
Gene name: hairy/enhancer-of-split related with YRPW motif 2
Probe: Hey2 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Absent 1C

Specimen 1F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar epithelium Ambiguous 1F Hardly detectable.
TS21: molar mesenchyme Ambiguous 1F Hardly detectable.

Specimen 1I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar Ambiguous 1I Almost negative, or at a quite low level.

Specimen 1L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: molar Ambiguous 1L Almost negative, or at a quite low level.

Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: inner enamel epithelium Present Regionally restricted 2C Restricted to the undifferentiatedundifferentiated inner enamel epithelium
TS24: molar mesenchyme Ambiguous 2C Absent, or at a very low level.

Specimen 2G/G': embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: inner enamel epithelium Present Regionally restricted 2G' , 2G Most intense expression in the undifferentiated inner enamel epithelium.
TS25: molar mesenchyme Ambiguous 2G' , 2G Absent, or at a very low level.

Specimen 2K/K': embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present Regionally restricted 2K , 2K' Peaked out expression in the undifferentiated inner enamel epithelium.
TS26: molar mesenchyme Ambiguous 2K , 2K' Absent, or at a very low level.

Specimen 3C/C': postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: molar epithelium Ambiguous 3C' , 3C Barely identified.
TS27: molar mesenchyme Ambiguous 3C' , 3C Barely identified.

Specimen 3G/G': postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: molar epithelium Ambiguous 3G , 3G' Barely identified.
TS27: molar mesenchyme Ambiguous 3G , 3G' Barely identified.

Specimen 3K/K': postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: molar epithelium Ambiguous 3K' , 3K Barely identified.
TS28: molar mesenchyme Ambiguous 3K' , 3K Barely identified.

Specimen 5C1/C2/C3/C4: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor enamel organ Present Regionally restricted 5C2 , 5C1 , 5C3 , 5C4 Expressed in the undifferentiated inner enamel epithelium in the apical bud, and barely detectable in preameloblasts and ameloblasts.
TS26: inner enamel epithelium Present Regionally restricted 5C1 , 5C4 , 5C3 , 5C2 Expressed in the undifferentiated inner enamel epithelium in the apical bud.
TS26: lower jaw incisor dental papilla Ambiguous 5C2 , 5C3 , 5C4 , 5C1 Barely detectable in mesenchymal cells.

Specimen 5G1: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: inner enamel epithelium Present Regionally restricted 5G1 Expressed in the undifferentiated inner enamel epithelium in the apical bud.
TS28: upper jaw incisor enamel organ Present Regionally restricted 5G1 Expressed in the undifferentiated inner enamel epithelium in the apical bud.
TS28: upper jaw incisor dental papilla Ambiguous 5G1 Barely detectable in mesenchymal cells.

Specimen 5G2: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor dental papilla Ambiguous 5G2 Barely detectable in mesenchymal cells.

Specimen 5K1: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: inner enamel epithelium Present Regionally restricted 5K1 Expressed in the undifferentiated inner enamel epithelium in the apical bud.
TS28: upper jaw incisor enamel organ Present Regionally restricted 5K1 Expressed in the undifferentiated inner enamel epithelium in the apical bud.
TS28: upper jaw incisor dental papilla Ambiguous 5K1 Barely detectable in mesenchymal cells.

Specimen 5K2: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor dental papilla Ambiguous 5K2 Barely detectable in mesenchymal cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory