About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:260416 Kibe K, et al., Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105
Assay type: RNA in situ
MGI Accession ID: MGI:6257001
Gene symbol: Hey1
Gene name: hairy/enhancer-of-split related with YRPW motif 1
Probe: Hey1 probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Absent 1B

Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar mesenchyme Present Regionally restricted 1E Expressed on the buccal side of the dental mesenchyme surrounding the tooth bud.
TS21: mandible Present 1E Expressed in osteoblasts.

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar Ambiguous 1H Almost negative, or at a quite low level.

Specimen 1K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: molar Ambiguous 1K Almost negative, or at a quite low level.

Specimen 1N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar epithelium Absent 1N
TS21: molar mesenchyme Present Regionally restricted 1N Expressed on the buccal side of the dental mesenchyme surrounding the tooth bud.

Specimen 2B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: molar dental papilla Present Regionally restricted 2B Expressed in the pulp horn region.
TS24: molar enamel organ Present Regionally restricted 2B Expressed in the inner enamel epithelium and preameloblasts.

Specimen 2F/F': embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: molar dental papilla Present Regionally restricted 2F , 2F' Expressed in the pulp horn region.
TS25: molar enamel organ Present Regionally restricted 2F , 2F' Increased expression in the inner enamel epithelium and preameloblasts.
TS25: inner enamel epithelium Present 2F , 2F' Increased expression.

Specimen 2J/J': embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: molar dental papilla Present Regionally restricted 2J' , 2J Most intense expression in the undifferentiated dental pulp cells beneath the odontoblasts.
TS26: molar enamel organ Present Regionally restricted 2J' , 2J Peak expression in the inner enamel epithelium and preameloblasts.
TS26: inner enamel epithelium Present 2J , 2J' Peak expression.

Specimen 3B/B': postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: molar dental papilla Strong Regionally restricted 3B' , 3B Expressed in the pulp horn region. Expressed in the subodontoblastic layer, not expressed in differentiated odontoblasts.
TS27: lower jaw incisor enamel organ Present 3B
TS27: upper jaw incisor dental papilla Present 3B

Specimen 3F/F': postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: molar dental papilla Strong Regionally restricted 3F' , 3F Expressed in the pulp horn region. Expressed in the subodontoblastic layer, not expressed in differentiated odontoblasts.

Specimen 3J/J': postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: molar dental papilla Present Regionally restricted 3J' , 3J Expressed in the pulp horn region. Expressed in the subodontoblastic layer, not expressed in differentiated odontoblasts.

Specimen 5B1/B2/B3/B4: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw incisor dental papilla Strong Regionally restricted 5B2 , 5B4 , 5B3 , 5B1 Expressed in the subodontoblastic layer beneath differentiated odontoblasts, not expressed in differentiated odontoblasts or undifferentiated dental mesenchymal cells near the apical bud.
TS26: lower jaw incisor enamel organ Weak Regionally restricted 5B2 , 5B4 , 5B1 Slightly expressed in preameloblasts.

Specimen 5F1: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor enamel organ Weak Regionally restricted 5F1 Slightly expressed in preameloblasts.

Specimen 5F2: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor dental papilla Strong Regionally restricted 5F2 Expressed in the subodontoblastic layer beneath differentiated odontoblasts, not expressed in differentiated odontoblasts.

Specimen 5J1: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor enamel organ Weak Regionally restricted 5J1 Slightly expressed in preameloblasts.

Specimen 5J2: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor dental papilla Strong Regionally restricted 5J2 Expressed in the subodontoblastic layer beneath differentiated odontoblasts, not expressed in differentiated odontoblasts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory