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Gene Expression Data
Assay Details
Assay
Reference: J:229950 Fujita M, et al., Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor. Mech Dev. 2016 Feb;139:65-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6236306
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175) (#9661)
Assay notes: The antibody recognized the cleaved form of the protein.
Results
Specimen 4Bd: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 4th branchial arch Trace 4Bd Few apoptotic cells were labeled.
Specimen 4Be: embryonic day 10.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally intact.
Structure Level Pattern Image Note
TS17: 4th branchial arch Trace 4Be The number of apoptotic cells did not increase in null embryos.
Specimen 4Bf: embryonic day 10.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally defective.
Structure Level Pattern Image Note
TS17: 4th branchial arch Trace 4Bf The number of apoptotic cells did not increase in null embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory