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Gene Expression Data
Assay Details
Assay
Reference: J:198578 Chervenak AP, et al., Spatiotemporal expression of zic genes during vertebrate inner ear development. Dev Dyn. 2013 Jul;242(7):897-908
Assay type: RNA in situ
MGI Accession ID: MGI:6226132
Gene symbol: Zic1
Gene name: zinc finger protein of the cerebellum 1
Probe: Zic1 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Specimens were postfixed in 4% paraformaldehyde, 0.2% glutaraldehyde.
Results
Specimen 6B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst mesenchyme Present Regionally restricted 6B Expression is in the mesenchyme surrounding the epithelium.
TS15: future hindbrain Present Regionally restricted 6B Expression is dorsal.
TS15: head mesenchyme Present Regionally restricted 6B Expression is in the mesenchyme between the ventral neural tube and the otic epithelium and adjacent to the dorsolateral side of the otocyst.
TS15: otocyst epithelium Absent 6B
Specimen 6H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst mesenchyme Present Regionally restricted 6H Expression is in the mesenchyme surrounding the epithelium.
TS17: hindbrain Present Regionally restricted 6H Expression is dorsal.
TS17: head mesenchyme Present Regionally restricted 6H Expression is in the mesenchyme between the ventral neural tube and the otic epithelium and adjacent to the dorsolateral side of the otocyst.
TS17: otocyst epithelium Absent 6H
Specimen 6N: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear mesenchyme Present Regionally restricted 6N Expression is in the mesenchyme surrounding the otic epithelium.
TS19: hindbrain Present Regionally restricted 6N Expression is dorsal.
TS19: head mesenchyme Present Regionally restricted 6N Expression is in cells located medially between the otic epithelium and the neural tube.
TS19: otocyst epithelium Absent 6N
Specimen 7B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 7B Expression is in cells in the mesenchyme adjacent to all portions of the otic epithelium except for the ventral portions of the ear.
TS20: inner ear epithelium Absent 7B
TS20: vestibulo-cochlear ganglion Absent 7B
Specimen 7B': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 7B' Expression is in cells in the mesenchyme adjacent to all portions of the otic epithelium except for the ventral portions of the ear.
TS20: inner ear epithelium Absent 7B'
Specimen 7H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 7H Expression is in cells in the mesenchyme adjacent to all portions of the otic epithelium except for the ventral portions of the ear.
TS21: inner ear epithelium Absent 7H
Specimen 7H': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 7H' Expression is in cells in the mesenchyme adjacent to all portions of the otic epithelium except for the ventral portions of the ear.
TS21: inner ear epithelium Absent 7H'
Specimen not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted Expression is dorsal.
Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted Expression is dorsal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory