Gene Expression Data
Assay Details
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Assay
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Reference:
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J:153643
Self M, et al., Six2 activity is required for the formation of the mammalian pyloric sphincter. Dev Biol. 2009 Oct 15;334(2):409-17
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6214816
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Gene symbol:
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Grem1
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Gene name:
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gremlin 1, DAN family BMP antagonist
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Results
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Specimen
E11.5 wildtype not shown:
embryonic day 11.5
(more  )
Specimen
E11.5 wildtype not shown:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: stomach mesenchyme |
Present |
Regionally restricted |
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Expression in mesenchymal layer of presumptive pyloric sphincter region.
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Specimen
E11.5 Six2-null not shown:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Six2tm1Gco/Six2tm1Gco
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: stomach mesenchyme |
Present |
Regionally restricted |
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Authors state the territory of expressing mesenchymal cells is smaller in the mutant.
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Specimen
5I:
embryonic day 12.5
(more )
Specimen
5I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5J:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Six2tm1Gco/Six2tm1Gco
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5K:
embryonic day 14.5
(more )
Specimen
5K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5L:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Six2tm1Gco/Six2tm1Gco
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: stomach pyloric region mesenchyme |
Present |
Regionally restricted |
5L
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Authors state expression levels appear normal but the domain of expressing mesenchymal cells is smaller in the mutant compared to wildtype embryos
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Analysis Tools