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Gene Expression Data
Assay Details
Assay
Reference: J:153643 Self M, et al., Six2 activity is required for the formation of the mammalian pyloric sphincter. Dev Biol. 2009 Oct 15;334(2):409-17
Assay type: RNA in situ
MGI Accession ID: MGI:6214815
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Results
Specimen E11.5 wildtype not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: stomach mesenchyme Present Regionally restricted Expression in mesenchyme of forestomach.
Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: stomach mesenchyme Present Regionally restricted 4A No expression in mesenchyme of presumptive pyloric sphincter region.
TS19: duodenum mesenchyme Present Regionally restricted 4A Expression in mesenchyme surrounding epithelium of presumptive duodenum.
Specimen 4B: embryonic day 11.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS19: duodenum mesenchyme Present Regionally restricted 4B Authors state expression pattern is not obviously affected in the mutant gut tube.
TS19: stomach mesenchyme Present Regionally restricted 4B Authors state expression pattern is not obviously affected in the mutant gut tube.
Specimen 4C,C': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: duodenum mesenchyme Present Widespread 4C' , 4C Expression in mesenchyme throughout stomach and small intestine.
TS20: stomach mesenchyme Present Widespread 4C' , 4C Expression in mesenchyme throughout stomach and small intestine.
TS20: stomach pyloric region Absent 4C' , 4C Expression excluded from presumptive pyloric sphincter region.
Specimen 4D,D': embryonic day 12.5; Six2tm1Gco/Six2tm1Gco (more )
Structure Level Pattern Image Note
TS20: stomach pyloric region Present 4D' , 4D Expression ectopically expanded into prresumptive pyloric sphincter region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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