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Gene Expression Data
Assay Details
Assay
Reference: J:149458 Gao Y, et al., Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Dev Biol. 2009 Apr 15;328(2):200-9
Assay type: RNA in situ
MGI Accession ID: MGI:6209620
Gene symbol: Fgfr2
Gene name: fibroblast growth factor receptor 2
Probe: Fgfr2 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen E13.5 +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: upper eyelid Present Authors state expression was similar in developing eyelid tissues in wild-type and Osr2-/- littermates at E13.5.

Specimen E13.5 -/- not shown: embryonic day 13.5; Osr2tm1Jian/Osr2tm1Jian (more )
Structure Level Pattern Image Note
TS21: upper eyelid Present Authors state expression was similar in developing eyelid tissues in wild-type and Osr2-/- littermates at E13.5.

Specimen 9G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper eyelid epithelium Present 9G
TS22: upper eyelid mesenchyme Present 9G

Specimen 9H: embryonic day 14.5; Osr2tm1Jian/Osr2tm1Jian (more )
Structure Level Pattern Image Note
TS22: upper eyelid epithelium Weak 9H Authors report decreased expression in both epithelium and mesenchyme in mutant embryos compared wild-type.
TS22: upper eyelid mesenchyme Weak 9H Authors report decreased expression in both epithelium and mesenchyme in mutant embryos compared wild-type.

Specimen 9J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: upper eyelid epithelium Present 9J
TS23: upper eyelid mesenchyme Present 9J

Specimen 9K: embryonic day 15.5; Osr2tm1Jian/Osr2tm1Jian (more )
Structure Level Pattern Image Note
TS23: upper eyelid epithelium Weak 9K Significantly decreased expression in eyelid epithelium and mesenchyme compared to wild-type embryos at this stage.
TS23: upper eyelid mesenchyme Weak 9K Significantly decreased expression in eyelid epithelium and mesenchyme compared to wild-type embryos at this stage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory